The Associated Press

CHARLOTTE, N.C. — Jairus Lyles could not suppress a smile, knowing that a school known more for chess than hoops had finally made it happen — a 16 ousting a 1 in March Madness.

The University of Maryland-Baltimore County stunned the sports world by pulling off the most shocking upset in college basketball history, hammering Virginia 74-54 on Friday night to become the first No. 16 seed ever to beat a No. 1 seed in the men’s NCAA Tournament.

UMBC secured its underdog legacy in sports lore, alongside Buster Douglas, the 1980 United States Olympic hockey team, Appalachian State football and Joe Namath’s Jets.

Virginia entered the NCAA Tournament as the No. 1 overall seed after going 31-2 in the regular season, including 20-1 in ACC competition.

The question was not whether they would win this game, but if they would get to the Final Four and win it all.

But UMBC — a team most glanced over when filling out their brackets — did not just beat Virginia, it dominated throughout the second half, dismantling the 201⁄2-point favorites by 20 points in the other direction. To put things in perspective, UMBC scored 53 points in the second half — one shy of how many Virginia scored in the entire game.

In a chaotic UMBC locker room after the game, players shouted: “All brackets gone! No perfect brackets! Put that in the news!”

Lyles scored 23 of his 28 points in the second half and the Retrievers cruised to an easy victory before racing off the floor together in their yellow-and-black uniforms, fingers pointed toward the ceiling.

“These are the moments that you dream of,” Lyles said. “It’s always exciting to make history.”

No. 1 seeds in the NCAA Tournament were 135-0.

Also Friday:

East Region

No. 2 Purdue 74, No. 15 CSU Fullerton 48: Purdue (29-6) center Isaac Haas broke his right elbow and will miss the rest of the NCAA Tournament. The 7-foot-2, 290-pound senior went down while taking a hard foul midway through the second half. Kyle Allman scored 21 for Fullerton (20-12).

No. 13 Marshall 81, No. 4 Wichita St. 75: SAN DIEGO — Jon Elmore scored 27 points and Marshall got its first NCAA Tournament victory. The Thundering Herd (25-10) had been 0-5 in the tourney, with its last appearance in 1987. Conner Frankamp scored 27 points for Wichita State (25-8).

No. 5 West Virginia 85, No. 12 Murray State 68: SAN DIEGO — Jevon Carter scored 21 points, had eight assists and six steals to lead West Virginia (25-10). Terrell Miller scored 27 points for Murray State (26-6).

No. 10 Butler 79, No. 7 Arkansas 62: SAN DIEGO — Kelan Martin scored 27 points and Kamar Baldwin added 24 to lift Butler (21-13). Jaylen Barford scored 15 points for Arkansas (23-12).

South Region

No. 2 Cincinnati 68, No. 15 Georgia State 53: NASHVILLE, Tenn. — Jarron Cumberland set career highs of 27 points and 11 rebounds as Cincinnati (31-4) recovered to beat Georgia State (24-11) after blowing a 10-point lead in the second half.

No. 7 Nevada 87, No. 10 Texas 83: NASHVILLE, Tenn. — Caleb Martin scored 18 points and made two huge 3-pointers in overtime as Nevada rallied for its first NCAA Tournament victory since 2007. Nevada (28-7) erased a 14-point, second-half deficit and tied it at 68 when Jordan Caroline hit one of two free throws with 3.8 seconds left in regulation. Kerwin Roach II had a career-high 26 points for Texas (19-15).

No. 9 Kansas St. 69, No. 8 Creighton 59: CHARLOTTE, N.C. — Barry Brown scored 18 points and Kansas State never trailed despite playing without top scorer Dean Wade. Mike McGuirl added 17 points for the Wildcats (23-11). Marcus Foster, thrown off the Kansas State team after the 2015 season for multiple violations of team rules, finished with five points on 2-of-11 shooting for Creighton (21-12).

Midwest Region

Michigan St. 82, Bucknell 78: DETROIT — Miles Bridges outlasted Zach Thomas, scoring 29 points and grabbing nine rebounds to lift Michigan State (30-4). Thomas fouled out on a technical with 6:06 left and finished with 27 points for Bucknell (25-10). He put on a show in the first half, scoring 20 points and making all three of his shots beyond the 3-point arc.

No. 4 Auburn 62, No. 13 College of Charleston 58: SAN DIEGO — Jared Harper made a clutch 3-pointer with 1:17 to go — his only basket of the game — to lift Auburn (26-7). Jarrell Brantley scored 24 for College of Charleston (26-8).

No. 5 Clemson 79, No. 12 New Mexico St. 68: SAN DIEGO — Shelton Mitchell scored a season-high 23 points, Gabe DeVoe had 22 and Clemson (24-9) shot 56 percent from the field while advancing out of the first round for the first time since 1997. Zach Lofton led New Mexico State (28-6) with 29 points.

No. 11 Syracuse 57, No. 6 TCU 52: DETROIT — Marek Dolezaj scored 17 points before fouling out to lead Syracuse (22-13). Both teams shot under 40 percent from the field. TCU (21-12) is still without an NCAA Tournament victory since 1987.

West Region

No. 1 Xavier 102, No. 16 Texas Southern 83: NASHVILLE, Tenn. — J.P. Macura scored 18 of his career-high 29 points in the first half, and Xavier routed Texas Southern (16-20) in its tournament opener. Trevon Bluiett added 26 points and Kerem Kanter had 24 for the Musketeers (29-5).

No. 2 North Carolina 84, No. 15 Lipscomb 66: CHARLOTTE, N.C. — Kenny Williams scored 18 points to lead defending national champion North Carolina (26-10).

No. 7 Texas A&M 73, No. 10 Providence 69: CHARLOTTE, N.C. — Admon Gilder scored 18 points to lead Texas A&M. Robert Williams and Tyler Davis both had double-doubles for the Aggies (21-12).

No. 9 Florida St. 67, No. 8 Missouri 54: NASHVILLE, Tenn. — Mfiondu Kabengele scored 14 points as Florida State (21-11) beat Missouri (20-13).