Guest Column

I’ve been planning a psilocybin manufacturing and service center ever since Oregon voters, including a majority of Deschutes County voters, passed Measure 109 in 2020. Given this strong public support and the remarkable clinical evidence supporting psilocybin’s use in a myriad of mental health conditions, I was extremely surprised when I heard that Commissioners Tony DeBone and Patti Adair were attempting to push through an opt-out measure, claiming they just didn’t know enough about the industry.

I scheduled a meeting with Tony and presented, in detail, what my business would look like. Here’s how minimal the impact will be. Here are the benefits to the community. Here are all of your concerns mitigated. He casually ignored me. Instead, he told me that he’d simply asked his wife, “Would you want a psilocybin business in our neighborhood?” Apparently, she responded with a hard negative.

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Ryan Reid lives in Bend.

(13) comments

kindergentlerbend

I keep hearing that the exceptional behavioral health and mental health professionals of Deschutes County feel hampered by the DeBone-Adair faction of the Commission.

In an era in which the United States is experiencing an epidemic of mental illness, shouldn’t we be using every proven tool (including psilocybin) in our armamentarium to help those who are suffering?

The two incumbent commissioners appear to be under the influence of habits of mind that harken to the Dark Ages. In fact, Ms. Adair has been seen distributing an essay purporting to solve America’s homelessness crisis, but which sports an artist’s rendering on its cover depicting a homeless man in the guise of a scary demon.

68836

I’m finding multiple studies on psilocybin used primarily in the treatment of depression and anxiety, especially those with a severe medical illness. Though some of these studies show promise, they are hampered by small sample sizes, lack of racial diversity, varying severity of disease, poor long-term follow-up, no placebo control group, and other biases. Nearly all these studies suggest additional future studies are needed. I am also finding that there are more robust upcoming studies currently accepting new patients, and results won’t be available for 1-2 years. So, I question that there exists “remarkable clinical evidence” to date supporting psilocybin as a true medicinal. I may be missing something, so if anyone knows of even one large, randomized, double-blind, placebo-controlled trial, that has been peer reviewed, and published in a reputable medical journal, please post the citation on this site. And is anyone aware of any proposals being sent to the FDA for psilocybin approval? Shouldn’t the FDA approve medications and their use based upon their unique doses, delivery systems, risks and benefits? Is the voting public equipped to make such a decision? Is there a study that shows 160 hours of training is sufficient for a drug that from what I see hasn’t met medical standards of research?

bravesoul coach

Double blind, peer reviewed and published in Jama!

https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2795625

68836

Please read this study. This is a study of only 93 patients concerning the use of psilocybin in a defined population of heavy drinkers with alcohol use disorder.

I have taken the liberty to cut and paste the investigators criticism of their own study:

“Limitations

Several limitations of the study warrant discussion. First, diphenhydramine was ineffective in maintaining the blind after drug administration, so biased expectancies could have influenced results. Control medications such as methylphenidate,42 niacin,2 and low-dose psilocybin1 likewise did not adequately maintain blinding in past psilocybin trials, so this issue remains a challenge for clinical research on psychedelics. Second, EtG samples, used to validate self-reported drinking outcomes, were available for only 53.8% of treated participants. Third, the study did not have adequate power to evaluate effects in subgroups, such as women, ethnic and racial minority groups, and individuals with psychiatric comorbidity, nor was it designed to identify causal mechanisms, optimal dosing, or predictors of treatment response. Fourth, the study population was lower in drinking intensity at screening than in most AUD medication trials, and results cannot be assumed to generalize to populations with more severe AUD. Fifth, the 2-group design does not permit evaluation of the effects of psychotherapy or the interaction between psychotherapy and medication. Sixth, the study does not provide information on the duration of the effects of psilocybin beyond the 32-week double-blind observation period, which is important given the often chronic, relapsing course of AUD. Further studies will be necessary to address these questions and many others concerning the use of psilocybin in the treatment of AUD.”

Further studies will be necessary . . . .

Nice try.

Please sent me another study. You are making my point!

bravesoul coach

This is not a medicine, so your question about FDA approving medications is not appropriate. The research shows that with simply 1-2 sessions the plant is highly effective. The research institutions doing this sessions have agreed on the proper dose for safety and minimal side effects.

68836

So let me get this right. You promote something to treat a medical condition(s) yet consider it not medicinal? Please explain.

Skittish

If it's "not medicine," then why are you promoting it as treating medical conditions? Does your poop smell nice too?

bravesoul coach

I just spent two days at a professional conference listening to all the research data. Oregon tax payers should be thrilled that we are addressing serious problems in our community (mental illness, substance abuse) and we have within our reach a solution that will cost the taxpayers NOTHING.

68836

I believe you attended a professional conference. Please provide me the medical qualifications of this event. In other words, were qualified CMEs made available for medical professionals? MDs, DOs, PAs, NPs, etc? Provide a link regarding the events of this conference including the qualifications of the presenters?

bravesoul coach

Their lack of interest in a solution that is effective, proven safe, and will cost the tax payers nothing is mind boggling.

80471

Commissioners Adair and DeBone are not the leaders we need to chart the path forward for Deschutes Country. It is time to replace them with leaders that understand that being elected to represent the citizens does not mean blocking progress and only supporting the minority and fringe views.

MF

When I spoke with Tony DeBone about climate change, he replied that he had googled it and didn’t learn much. I exclaimed “your knowledge of climate change comes from a google search?!?!” I was flabbergasted and he was, well, not flabbergasted.

373749

Well put!

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